Journal of Bioscience and Bioengineering Vol. 103, No. 1 (January 2007)  Cover

Effect of polymer surface properties on morphology, growth rate, and differentiation of mouse embryonic stem (ES) cells.

Alkaline phosphatase staining of mouse ES cells cultured on different photoimmobilized polymers: an anionic polymer (top, left), a cationic polymer (bottom, left), a zwitterionic polymer (top, right), and a biological polymer (bottom, right). The red color indicates the cells stained for alkaline phosphatase, a marker of the undifferentiated state of the cells. The polymer surface properties can affect the morphology, growth rate, and differentiation of mouse ES cells.

Related article: Konno, T., Kawazoe, N., Chen, G., and Ito, Y., "Culture of mouse embryonic stem cells on photoimmobilized polymers", J. Biosci. Bioeng., vol. 102, 304-310 (2006).