Journal of Bioscience and Bioengineering Vol. 103, No. 3  (March 2007) Cover

Macrophage network theory.

Information related to the external environment and stimuli could be transferred from local macrophages to other tissue macrophages. Authors hypothesized the existence of a network formed by tissue macrophages and termed this putative communication network a macrophage network. Based on this theory, lipopolysaccharide derived from Pantoea agglomerans can be applied to health care.      

Related article: Kohchi, C., Inagawa, H., Nishizawa, T., Yamaguchi, T., Nagai, S., and Soma, G., "Applications of lipopolysaccharide derived from Pantoea agglomerans (IP-PA1) for health care based on macrophage network theory", J. Biosci. Bioeng., vol. 102, 485-496 (2006).