Journal of Bioscience and Bioengineering  coverThe Journal of Bioscience and Bioengineering (JBB) is an international journal devoted to the rapid publication of papers describing original research in the field of biotechnology. JBB encourages and publishes new concepts in technology/methodology that significantly advance the understanding of bioscience and bioengineering and contribute to the development of chemical, pharmaceutical, medical, food, and agricultural industries. The Editorial Committee makes its best efforts to provide expeditious, rigorous and fair peer-review, ensuring the high quality of articles published in JBB.

JBB is published monthly (2 vols. in 12 issues) by the Society for Biotechnology, Japan and distributed outside Japan by Elsevier. Online version is available in ScienceDirect. The journal was first published in 1923, originally being named Jyozogaku Zasshi (in Japanese) and then renamed Hakkokogaku Zasshi (in Japanese) (1944), Journal of Fermentation Technology (1973), and Journal of Fermentation and Bioengineering (1989). It was given the current name in 1999. JBB has established itself as one of the most influential biotechnology journals and is now highly appreciated by scientists throughout the world.

JBB is abstracted/indexed in BIOSIS, Chemical Abstracts, Current Contents, EMBASE/Excerpta Medica, Elsevier BIOBASE/Current Awareness in Biological Sciences, ISI Biotechnology Citation Index, and MEDLINE/PubMed.

Print ISSN 1389-1723
Online ISSN 1347-4421
CODEN: JBBIF6
Impact Factor: 2.3 (2023)

Vol. 138 Cover Illustration

Chinese hamster ovary (CHO) cells are currently the most widely used host cells in the production of biopharmaceuticals such as antibody
drugs, and it is known that the karyotype of CHO cells can be easily changed. The effect of the karyotype changeability of CHO cells on the production of recombinant proteins is an interesting subject. The photograph shows the results of karyotyping of CHO cells with increased chromosome number using the multicolor FISH method, with each chromosome number indicated by a different pseudocolor.

For more information regarding this work, read the article: Noriko Yamano-Adachi, Hirofumi Hata, Yuto Nakanishi, Takeshi Omasa, “Effects of genome instability of parental CHO cell clones on chromosome number distribution and recombinant protein production in parent-derived subclones”, J. Biosci. Bioeng., volume 137, issue 1, pages 54–63 (2024) (Copyright@2024 The Society for Biotechnology, Japan).

 

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